Anti-arrhythmics

TerraQSAR-LOGPTM computed octanol/water partition coefficients (CLOGPs).

For other toxicity and effect values, such as mammalian (rat/mouse) intravenous LD50, fish (fathead minnow) 96-hr LC50, estrogen receptor binding affinity (RBA), use TerraQSAR-RMIV, TerraQSAR-FHM, and TerraQSAR-E2-RBA programs, or consult TerraBase Inc.

NAME CAS FORMULA MWTerraQSAR - LOGP
timonacic 444-27-9 C4H7NO2S 133.17
-1.83
mexiletine 31828-71-4 C11H17NO 179.26
2.15
meobentine 46464-11-3 C11H17N3O 207.28
3.45
alinidine 33178-86-8 C12H13Cl2N3 270.16
3.45
palatrigine 98410-36-7 C12H14Cl3N5 334.64
-0.08
dexsotalol 30236-32-9 C12H20N2O3S 272.37
0.24
dicarbine 17411-19-7 C13H18N2 202.30
2.06
cicletanine 89943-82-8 C14H12ClNO2 261.71
2.46
simendan 131741-08-7 C14H12N6O 280.29
1.93
nadoxolol 54063-51-3 C14H16N2O3 260.29
1.96
eprobemide 87940-60-1 C14H19ClN2O2 282.77
0.95
indenolol 60607-68-3 C15H21NO2 247.34
3.09
recainam 74738-24-2 C15H25N3O 263.38
2.21
melperone 3575-80-2 C16H22FNO 263.36
3.31
capobenic acid 21434-91-3 C16H23NO6 325.36
0.65
pincainide 83471-41-4 C16H24N2O 260.38
2.20
dazolicine 61477-97-2 C17H24ClN3S 337.92
3.38
bisaramil 89194-77-4 C17H24Cl2N2O2 359.30
3.23
tilisolol 85136-71-6 C17H24N2O3 304.39
1.07
cibenzoline 53267-01-9 C18H18N2 262.36
5.42
carcainium chloride 1042-42-8 C18H22ClN3O2 347.85
3.30
pranolium chloride 42879-47-0 C18H26ClNO2 323.86
-1.58
bumecaine 30103-44-7 C18H28N2O 288.43
2.26
benzobarbital 744-80-9 C19H16N2O4 336.35
1.47
tolamolol 38103-61-6 C19H24N2O4 344.41
3.03
drobuline 58473-73-7 C19H25NO 283.41
3.62
berlafenone 18965-97-4 C19H25NO2 299.41
4.46
milacainide 141725-10-2 C19H25N3O 311.43
3.21
emilium tosilate 30716-01-9 C19H27NO4S 365.49
-1.94
almokalant 123955-10-2 C19H30N2O2S 350.52
3.43
amafolone 50588-47-1 C19H31NO2 305.46
3.68
tedisamil 90961-53-8 C19H32N2 288.48
1.91
pentisomide 96513-83-6 C19H33N3O 319.49
2.58
artilide 133267-19-3 C19H34N2O3S 370.56
0.24
quifenadine 10447-39-9 C20H23NO 293.41
3.78
cetiedil 14176-10-4 C20H31NO2S 349.54
6.45
nizofenone 54533-85-6 C21H21ClN4O3 412.88
3.86
rilmakalim 132014-21-2 C21H23NO5S 401.48
2.71
ambasilide 83991-25-7 C21H25N3O 335.45
1.39
ersentilide 125279-79-0 C21H26N4O5S 446.53
1.66
disopyramide (base) 3737-09-5 C21H29N3O 339.48
2.58
bunaftine 32421-46-8 C21H30N2O 326.48
1.95
bucainide 51481-62-0 C21H35N3 329.53
3.20
lorajmine 47562-08-3 C22H27ClN2O3 402.92
1.68
sequifenadine 57734-69-7 C22H27NO 321.46
3.97
modecainide 81329-71-7 C22H28N2O3 368.48
3.20
transcainide 88296-62-2 C22H35N3O2 373.54
2.79
azimilide 149908-53-2 C23H28ClN5O3 457.96
2.84
pirolazamide 39186-49-7 C23H29N3O 363.50
3.74
eproxindine 83200-08-2 C23H29N3O3 395.50
3.44
diprafenone 81447-80-5 C23H31NO3 369.50
4.41
moxaprindine 53076-26-9 C23H32N2O 352.52
4.86
fosinoprilat 95399-71-6 C23H34NO5P 435.50
5.21
actisomide 96914-39-5 C23H35N3O 369.55
3.12
cyheptropine 602-40-4 C24H27NO2 361.48
3.44
siratiazem 138778-28-6 C24H30N2O4S 442.58
2.70
falipamil 77862-92-1 C24H32N2O5 428.53
2.65
droprenilamine 57653-27-7 C24H33N 335.53
4.79
bepridil 64706-54-3 C24H34N2O 366.55
4.85
oxiramide 13958-40-2 C25H34N2O2 394.56
4.26
alprafenone 124316-02-5 C25H35NO4 413.56
4.26
piprofurol 40680-87-3 C26H33NO6 455.55
3.70
tiapamil 57010-31-8 C26H37NO8S2 555.71
-0.15
pyrinoline 1740-22-3 C27H20N4O 416.48
3.50
gallopamil 16662-47-8 C28H40N2O5 484.64
3.79
fenoxedil 54063-40-0 C28H42N2O5 486.65
4.12
levosemotiadil, (S)-isomer of semotiadil 116476-16-5 C29H32N2O6S 536.65
2.70
semotiadil, (R)-isomer 116476-13-2 C29H32N2O6S 536.65
2.70
bucromarone 78371-66-1 C29H37NO4 463.62
3.77
ropitoin 56079-81-3 C30H33N3O3 483.61
4.87
proscillaridin 466-06-8 C30H42O8 530.66
1.89
dronedarone 141626-36-0 C31H44N2O5S 556.77
3.07
quinetalate 5714-76-1 C38H57N5O7 695.90
1.07
prednisolone steaglate 5060-55-9 C41H64O8 684.95
1.98
deslanoside 17598-65-1 C47H74O19 943.09
3.85

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